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Witcha Imaram. Study of the reaction conditions mediated synthesis of 4-thiazolidinone derivatives by one-pot three-component reaction. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2016.
Study of the reaction conditions mediated synthesis of 4-thiazolidinone derivatives by one-pot three-component reaction
Name: Natsima Nuammee
Organization :
Kasetsart University. Faculty of Science
Name: Witcha Imaram
Organization :
Kasetsart University. Faculty of Science
Email :
witcha.i@ku.ac.th
LCSH:
Organic compounds
-- Synthesis
Abstract:
4-Thiazolidinone, a class of heterocyclic compounds, is a biologically important
scaffold that exhibits diverse biological activities. Some of the well-known biological
responses attributed to these compounds are anti-inflammatory, antiviral, anticonvulsant,
antifungal, and antibacterial. Due to their potential as a new class of drugs, 4-thiazolidinones
have attracted considerable attention from various research groups to explore the potential
synthetic modification and design more new derivatives to study their activities. In this work,
we will report the study of three synthetic strategies that have been employed to synthesize
the targeted 4-thiazolidinone derivatives. Those methods are 1. DCC (N, N-dicyclohexylcarbodiimide)
catalyzed,7 2. silica gel promoted8 one-pot three-component reaction of amine,
carbonyl compound, and mercaptoacetic acid. The results from each strategy will be
discussed. These experiments would allow us to design the most effective method to
synthesize a library of 4-thiazolidinone derivatives for further biological activity screening
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2016
Modified:
2023-01-12
Issued:
2023-01-12
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn and Chulalongkorn University Faculty of science. Pure and Applied Chemistry International Conference (PACCON 2016) (pp.1556-1561). Bangkok : Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.039786 วินาที
Natsima Nuammee
| Title | Contributor | Type |
|---|---|---|
| Study of the reaction conditions mediated synthesis of 4-thiazolidinone derivatives by one-pot three-component reaction
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Natsima Nuammee;Witcha Imaram | บทความ/Article |
Witcha Imaram
| Title | Contributor | Type |
|---|---|---|
| A new synthetic route to 5-tert-butoxycarbonyl 5-methyl-1-pyrroline N-oxide
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Chaiyawat Aonsri;Boonsong Kongkathip;Witcha Imaram | บทความ/Article | |
| Study of the reaction conditions mediated synthesis of 4-thiazolidinone derivatives by one-pot three-component reaction
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Natsima Nuammee;Witcha Imaram | บทความ/Article |